[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_class=”infographic” _builder_version=”3.22.2″ custom_margin=”55px||” custom_padding=”|0px||0px” transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row make_equal=”on” module_class=”rounded” _builder_version=”3.25″ background_image=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/wallpaper_health.gif” parallax=”on” custom_padding=”30px||30px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Infographic: The Pandemic\u2019s Effect: What We\u2019re Hearing From Our Health Grantees” module_class=”rounded” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark” custom_padding=”10px|30px|30px|30px” use_border_color=”off” global_colors_info=”{}”]<\/p>\n
THE PANDEMIC’S EFFECT<\/p>\n
What We Heard From Grantees<\/p>\n
Investigators and trainees faced employment, educational and financial uncertainties.<\/p>\n
![\"\"](\"https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/HealthIcon-Researcher.png\")
<\/p>\n\t\t\t\t<\/div>
![\"\"](\"https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/icon_covid3.png\"){kind=icon}
<\/p>\n
COVID-19 restrictions and lab shutdowns slowed IBD research progress.<\/p>\n\t\t\t\t<\/div>
Female scientists with young children had less time to submit papers and seek funding.<\/p>\n
![\"\"](\"https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/icon_family-blue.png\"){kind=icon}
\n\t\t\t\t<\/div>
Adapting To Uncertainty<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
The pandemic took a tremendous toll on researchers and their cutting-edge work on Inflammatory Bowel Disease (IBD). Principal investigators faced a new learning curve to guide and support their teams through an unprecedented time. Our\u00a0Health grantees relayed wide-ranging stories from adapting their labs to non-IBD research to temporarily shutting down. Clinicians left their labs to meet urgent patient care needs, and other grantees pivoted their research to direct pandemic response. But\u00a0pre-existing inequities exacerbated the impact on female as well as Black and Latinx researchers.<\/p>\n
Listening was crucial to helping the Foundation understand how to sustain our scientific community through the uncertainty. Our Scientific Advisory Board<\/a> provided critical guidance and pivoted along with our staff and Board to focus on flexibility and responsiveness. At the pandemic\u2019s outset, due to the uncertain state of research, we made the difficult decision to pause the 2020 Innovator Awards cycle. The Foundation immediately offered no-cost extensions to current Innovator Award grantees along with grants of up to $50,000 to support labs.<\/p>\n In response to what we heard from grantees about their needs, we shifted our 2021 Innovator Awards timeline to provide earlier access to funding. This change allows labs to plan and retain post-docs and graduate students in June. The pandemic will have long-term impacts on the field and we remain committed to our Health grantees and safeguarding their groundbreaking work to advance IBD research<\/a>.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n “Our call to action as a funder was to reach out, listen and be attuned to the human impact on our grantee community. Then we responded quickly and strategically, with as much flexibility and support as possible.”<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}” column_structure=”1_3,2_3″][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Laura Wilson” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Laura Wilson, PhD<\/strong>, Director, Health Strategy & Ventures<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575-Image_5-researchers-in-lab.jpg” align_tablet=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ use_border_color=”off” global_colors_info=”{}” align_phone=”center”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_font=”||||||||” header_5_font=”||||||||” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo credit: Hinterhaus Productions, Getty Images<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Addressing Equity In Biomedical Research” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Addressing Equity In Biomedical Research<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”3.27.4″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n The huge institutionalized systems for advancing research and delivering health care are overwhelmingly white, male and driven by conscious and unconscious bias. Over the years, we\u2019ve taken steps to advance gender equity. In 2020, a reckoning emerged in both academia and philanthropy to also address racial inequities. The Rainin Foundation is engaged in this movement alongside other biomedical research funders.<\/p>\n We acknowledge how racism denies access to resources, including funding for scientists who are Black, Indigenous and people of color. In 2020,\u00a0we embarked on a journey of inquiry into the role that the Rainin Foundation can play to address racial disparities<\/a>\u00a0in the biomedical enterprise. We began with honest conversations that leveraged the diverse expertise and leadership of our\u00a0Scientific Advisory Board<\/a>. Our work will continue by listening to our grantees and engaging partners to help us reach beyond our existing networks. Collecting grantee demographic data will help us monitor our own practices and better understand the state of our field. We are committed to doing our part to advance racial equity in the biomedical research field\u2014a key step to advancing science.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]”Diversity makes science better. It\u2019s incumbent upon all of us\u2014funders, researchers and those in academia\u2014to be antiracist agents of change. It\u2019s time to acknowledge racist practices and dismantle the systems that promote disparities for our colleagues of color, especially Black scientists.”[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”||50px” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}” column_structure=”1_3,2_3″][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Dr. Tejal Desai” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Dr. Tejal Desai<\/strong>, University of California, San Francisco, and a co-author of “Fund Black Scientists”<\/u><\/a><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”30px|30px|30px|30px” custom_css_main_element=”border-radius: 20px;” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Gender Equity In Biomedical Research” _builder_version=”4.14.8″ text_font_size=”1em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” background_layout=”dark” module_alignment=”center” hover_enabled=”0″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n MULTI-GENERATIONAL INSIGHTS<\/p>\n Gender Equity In Biomedical Research<\/p>\n [\/et_pb_text][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/Health_Gender_Equity_Three-Researchers.jpg” url=”https:\/\/krfoundation.org\/multi-generational-insights-gender-equity-in-biomedical-research\/” url_new_window=”on” align_tablet=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ custom_margin=”||5px” global_colors_info=”{}” align_phone=”center”][\/et_pb_image][et_pb_text admin_label=”caption” _builder_version=”4.14.8″ text_font=”||||||||” text_font_size=”0.8em” text_line_height=”3em” header_font=”||||||||” header_5_font=”||||||||” header_5_font_size=”15px” header_5_line_height=”1.6em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark” custom_margin=”-10px||” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” custom_padding_last_edited=”on|phone” hover_enabled=”0″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n Photos courtesy of the researchers<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Creating Opportunities for Connection” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Creating Opportunities For Connection<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n By spring it became clear that an in-person Innovations Symposium event would not be possible. At the same time, we were hearing about the pandemic\u2019s toll on trainees and early career researchers. Their work was suffering from isolation and the lack of opportunities to solicit feedback. We reimagined the Symposium to highlight their roles in advancing IBD research and to connect our grantee community.<\/p>\n Our 2020 Socially Distant Symposium was designed specifically for our grantees, convening more than 60 researchers over three half-days in November. The agenda included presentations by both Principal Investigators and trainees. Topics included milk-derived exosome therapies, the use of molecular imaging devices<\/a>, non-surgical therapies using regenerative medicine<\/a> and mechanisms underlying our sensation of pain<\/a>. This event opened new avenues for us to support innovative research and collaboration. It laid the groundwork for creating our 2021 Symposium<\/a> in July, which will be virtual and open to researchers worldwide.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]”This was one of my best virtual meeting experiences. Your organizers and moderators created a lively exchange and I enjoyed the diversity of topics. I learned quite a lot from many great talks.”[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}” column_structure=”1_3,2_3″][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Christian Brendel” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Christian Brendel, PhD<\/strong>, Dana Farber Cancer Institute\/Boston Children’s Hospital<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575-dr-Kamada.jpg” align_tablet=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ use_border_color=”off” global_colors_info=”{}” align_phone=”center”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_font=”||||||||” header_5_font=”||||||||” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo credit: Mitch Tobias<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Revealing Our Funding Impact” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Revealing Our Funding Impact<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n The rapid mobilization of science and technology to develop effective COVID-19 vaccines is an unambiguous achievement. But that extraordinary pace was possible only after decades of investment in basic immunology and vaccinology research<\/a>. Scientific results like this often emerge many years after funding has ended\u2014especially for early stage and basic research. Yet measuring the impact of biomedical research funding is critical to advancing effective, strategic grantmaking.<\/p>\n The Rainin Foundation\u2019s powerful new evaluation tool\u2014Researchfish\u2014is embraced by a global community of funders, research institutions and scientists. Its integrated platform enhances our ability to both evaluate our philanthropic impact and ease reporting burdens for grantees. We launched the new system for our grantee reporting in May. As we accumulate data on grantee progress, we will gain a longitudinal understanding of our impact on research and innovation.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]”Collaboration with clinicians and researchers in other fields is absolutely necessary to develop treatment strategies. I\u2019m working with an IBD doctor and a dietician right now.”[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}” column_structure=”1_3,2_3″][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Nobuhiko Kamada” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Nobuhiko Kamada, PhD<\/strong>, University of Michigan<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575-Image-Health-Woman-Holding-Tray.jpg” align_tablet=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ use_border_color=”off” global_colors_info=”{}” align_phone=”center”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_font=”||||||||” header_5_font=”||||||||” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo credit: Solskin, Getty Images<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Bringing Solutions Closer to Patients” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Bringing Solutions Closer To Patients<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n Despite limitations wrought by the pandemic, dedicated researchers continued their work to transform the prediction and prevention of IBD. In December, the Food and Drug Administration (FDA) granted orphan drug designation for TP-317 as a small molecule, oral therapy for treatment of pediatric ulcerative colitis. Thetis Pharmaceuticals, recipient of a Program Related Investment by the Foundation, developed this novel therapy. In preclinical models of IBD, the active agent in TP-317 resolved inflammation and promoted tissue repair without suppressing the immune system. This medication holds promise for people with IBD as well as acute respiratory distress syndrome (ARDS), a severe inflammatory condition of COVID-19.<\/p>\n Our Synergy Awards, which support cross-disciplinary research teams, included new and continued support for translational research projects that bring solutions closer to patients. Here are some highlights:<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n “The Synergy Award gives us the unique opportunity to partner with a bio-engineering lab to tackle an out-of-the-box concept applying cell-free DNA diagnostics to IBD. If successful, this technology will provide us with an innovative blood test to track intestinal inflammation and microbial translocation, helping to manage and treat IBD in the clinic.”<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}” column_structure=”1_3,2_3″][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Randy Longman” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Randy Longman, MD, PhD<\/strong>, Weill Cornell Medicine<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575-Imge-jeffrey-lab.jpg” align_tablet=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ use_border_color=”off” global_colors_info=”{}” align_phone=”center”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_font=”||||||||” header_5_font=”||||||||” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo credit: Lori Halloran<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Investing In Cross-Disciplinary Research: 2020 Grantees” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Investing In Cross-Disciplinary Research: [\/et_pb_text][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” global_colors_info=”{}” column_structure=”2_5,3_5″][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”invested $4 million” _builder_version=”3.27.4″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Health grantmaking supports groundbreaking ideas that have the potential to dramatically transform the prediction and prevention of Inflammatory Bowel Disease.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”audit text” _builder_version=”3.27.4″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Note: Financials are subject to audit verification.<\/em><\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/TP-pie-Chart-Health-2020.gif” align_tablet=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ global_colors_info=”{}” align_phone=”center”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][et_pb_text admin_label=”Innovator Awards” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n INNOVATOR AWARDS<\/strong><\/p>\n Due to the pandemic\u2019s uncertainty on research, we paused our 2020 Innovator Awards cycle, and responded by providing additional funding support and no-cost extensions to current grantees. This grant program resumes in 2021 to support an international pool of early-career and seasoned researchers to study untested ideas that could lead to breakthrough discoveries about IBD.\u00a0View more information<\/strong><\/a>\u00a0about this grant program.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Synergy Awards” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n SYNERGY AWARDS<\/strong><\/p>\n Grants support cross-disciplinary teams of researchers who are pursuing collaborative projects aimed at improving the prediction and prevention of IBD.\u00a0The 2021 Synergy Awards cycle has been put on hold. View more information<\/strong><\/a>\u00a0about these grants.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Markus Neurath, MD, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg; Klaus Gerwert, PhD, Ruhr-Universit\u00e4t Bochum; and Arif Ekici, PhD, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg<\/p>\n Jeremiah Faith, PhD, Mount Sinai; Purna Kashyap, MBBS, Mayo Clinic; and Laura Raffals, MD, Mayo Clinic<\/p>\n Nobuhiko Kamada, PhD, University of Michigan; Peter Higgins, MD, PhD, University of Michigan; and Theresa Han-Markey, MS, RD, University of Michigan<\/p>\n\t\t\t\t<\/div> Gwendalyn Randolph, PhD, Washington University in St. Louis; Michael Davis, PhD, University of Missouri; and Alison Kohan, PhD, University of Pittsburgh<\/p>\n Shimon Reif, MD, Hadassah Medical Center; Yehuda Chowers, MD, Rambam Health Care Campus; and Maria Abreu, MD, University of Miami<\/p>\n Amy Lightner, MD, Cleveland Clinic; Miguel Regueiro, MD, Cleveland Clinic; and Yan Li, MD, Cleveland Clinic<\/p>\n\t\t\t\t<\/div> [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Synergy Awards – Continued Support” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” use_border_color=”off” global_colors_info=”{}”]<\/p>\n SYNERGY AWARDS – CONTINUED SUPPORT<\/strong><\/p>\n Research teams who demonstrate significant progress toward their original goals are eligible for up to two years of additional support.\u00a0View more information<\/strong><\/a>\u00a0about these grants.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Charles Elson, MD, University of Alabama at Birmingham and Phillip Stafford, PhD, Arizona State University<\/p>\n Howard Hang, PhD, Rockefeller University; Ken Cadwell, PhD, New York University; and Thomas Walz, PhD, Rockefeller University<\/p>\n Kate Jeffrey, PhD, Massachusetts General Hospital; Naama Geva-Zatorsky, PhD, Technion \u2013 Israel Institute of Technology; Irah King, PhD, McGill University; and Corinne Maurice, PhD, McGill University<\/p>\n\t\t\t\t<\/div> Garry Nolan, PhD, Stanford University; Sarah Streett, MD, Stanford University; Stephan Rogalla, MD, Stanford University; Aaron Mayer, MS, Stanford University<\/p>\n Thaddeus Stappenbeck, MD, PhD, Cleveland Clinic and Michael Diamond, MD, PhD, Washington University\n\t\t\t\t<\/div> [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Explore” _builder_version=”3.27.4″ text_font=”Georgia||||” text_font_size=”20″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” custom_padding_last_edited=”on|phone” use_border_color=”off” border_color=”#ffffff” border_style=”solid” saved_tabs=”all” global_colors_info=”{}”]Explore the Foundation\u2019s website to learn more about our Health program<\/a> and meet our\u00a0staff<\/a> and Board members<\/a>.[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ z_index_tablet=”500″ global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”||0px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Turning Points 2020″ module_class=”tpfoot” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n <\/p>\nDiverse perspectives are crucial to achieving scientific breakthroughs for patients.<\/h5>\n
Three scientists\u2014Dr. Bana Jabri, Dr. Shruti Naik and Ansen Burr\u2014offer their perspectives and insights for ways to advance along the path toward equity. The Kenneth Rainin Foundation is committed to addressing barriers that limit opportunity for women in science.\u00a0<\/h5>\n
Dr. Nobuhiko Kamada and his lab at the University of Michigan are researching the bacterial troublemakers that contribute to IBD pathogenesis, specifically Escherichia coli. Continue reading ><\/a><\/strong><\/h5>\n
The Rainin Foundation supports research that could improve the prediction and prevention of IBD.<\/h5>\n
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Dr. Kate Jeffrey and members of Jeffrey Lab at Massachusetts General Hospital are using CLIP (Cross-linking immunoprecipitation) to identify and sequence individual viruses that could be important for gut health or influential during inflammation.<\/h5>\n
\n2020 Grantees<\/p>\nThe Rainin Foundation invested over $4 million in 2020 to support IBD research.<\/h2>\n