[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Rothlin.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Photo credit: Harold Shapiro<\/p>\n
Dr. Carla Rothlin, Yale School of Medicine, shared reflections about the pandemic\u2019s impact<\/u><\/a> and her lab\u2019s efforts to adapt while advancing groundbreaking ideas in Inflammatory Bowel Disease (IBD) research.<\/h5>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Navigating Constraints on Innovation ” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Navigating Constraints On Innovation<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
The pandemic has created ongoing uncertainty for everyone in biomedical research, inflicting a widespread personal and professional toll on researchers. Pre-existing inequities exacerbated these hardships for female as well as Black and Latinx researchers. The impacts have differed depending in part on geographic location and institutional resources. These have been compounded by COVID restrictions and access to vaccines, which vary widely in different parts of the world. Researchers shared how these conditions affected their capacity to innovate<\/a> and advance their work. Many continued to express concern about their ability to regain the same high level of research as before.<\/p>\nYet researchers continued working\u2014analyzing data, publishing papers<\/a> and troubleshooting technical challenges. They created new platforms for connecting and sharing expertise more widely, innovated new strategies in clinical studies and contributed to COVID-19 research and treatment.<\/p>\nTo support our grantees, the Rainin Foundation stayed connected and listened carefully to what they needed. We looked for ways we could tailor financial and other supports that were sensitive to their distinct challenges. And we offered flexibility through no-cost extensions and top-up funding with minimal application requirements.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”10px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
\n“As funders, it\u2019s imperative for us to continue to listen to our grantee community to understand the best ways to support them. Their students and trainees are especially vulnerable, yet essential to the future of science.”<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”||30px|50px” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Laura Wilson” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
\u2014Laura Wilson, PhD<\/strong>, Director, Health Strategy & Ventures<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_HealthTejalDesai.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Photo courtesy of Tejal Desai<\/p>\n
Tejal Desai, PhD, brings valuable expertise and leadership to our Scientific Advisory Board and is an influential voice in science. With her bioengineering co-authors, Dr. Desai published a strong call for racial equity in federal funding in Cell<\/u><\/a>.<\/u><\/h5>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Advancing Equity To Advance Science” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Advancing Equity To Advance Science<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”3.27.4″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
\nThe Rainin Foundation\u2019s commitment to equity extends across our organization and includes a sustained process of internal learning. Our focus on gender parity in Health grantmaking continued with our 2021 Innovator Awards<\/a>. Four of the eight research teams that received funding are led by women. Our 2021 Innovations Symposium<\/a> featured gender parity in the presenting speakers, including academic and industry leaders who identify as women. We remain committed to elevating underrepresented researchers to address persistent gender bias and gaps that affect medical research.<\/p>\nTo build more equitable programs and practices, we began collecting grantee demographic data with applications for our 2022 Innovator Awards. Our Health program staff also collaborated with our Scientific Advisory Board<\/a> to gain their insights and expertise. In September, we convened members to examine how we can contribute to advancing racial and gender equity in biomedical research. There was strong consensus on the overall need to focus earlier in the academic and research pipeline. We explored ways to target younger scientists of color who are aspiring to research positions during their graduate studies.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”30px||30px|” custom_padding=”30px|30px|30px|30px” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Celebrating A 2021 Nobel Laureate” _builder_version=”4.14.8″ text_font_size=”1em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” background_layout=”dark” module_alignment=”center” hover_enabled=”0″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
GRANTEE MILESTONE<\/p>\n
Celebrating A 2021 Nobel Laureate<\/p>\n
[\/et_pb_text][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Julius.jpg” url=”https:\/\/krfoundation.org\/rainin-foundation-celebrates-a-2021-nobel-laureate-among-its-health-grantees\/” url_new_window=”on” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ custom_margin=”||5px” z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”caption” _builder_version=”4.14.8″ text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark” custom_margin=”-10px||” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” custom_padding_last_edited=”on|phone” hover_enabled=”0″ z_index_tablet=”500″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
Photo credit: Noah Berger<\/p>\n
Dr. David Julius, professor and chair of the Department of Physiology and the Morris Herzstein Chair in Molecular Biology and Medicine at University of California, San Francisco, was awarded the 2021 Nobel Prize<\/u><\/a> for his research into the molecular basis for the sensations of pain and pressure. He received the prize jointly with Ardem Patapoutian, PhD, a molecular biologist at Scripps Research. Dr. Julius\u2019 groundbreaking work has significant implications for people living with IBD.<\/h5>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Improving Lives Through Novel Research” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Improving Lives Through Novel Research<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
The Rainin Foundation\u2019s Health grantmaking aims to improve the lives of IBD patients and to one day cure the disease. In May, we awarded $1.2 million through our Innovator Awards program, investing in early career and veteran IBD researchers alike. Grantees are pursuing a range of patient-focused ideas<\/a> with clinical implications from treating pain and inflammation to achieving lasting remission. Some highlights include:<\/p>\n\n- Isaac Chiu, PhD<\/strong><\/a>, Harvard Medical School, and his team are seeking to characterize the role of neurons that mediate pain in IBD, and to determine whether inhibiting or activating these neurons leads to changes in the gut that can treat pain and inflammation.<\/li>\n
- Shruti Naik, PhD,<\/strong><\/a> and\u00a0Daniel Rosenblum, PhD<\/strong><\/a>, New York University Grossman School of Medicine, are investigating how intestinal stem cell niches change over the course of disease and use this information to achieve lasting remission in IBD.<\/li>\n
- Anna Katharina (Katja) Simon, PhD<\/strong><\/a> and\u00a0Fiona Powrie, PhD<\/strong><\/a>, University of Oxford, are using their research to target the association of abdominal fat tissue in many Crohn\u2019s disease patients with the promotion of pro-repair mechanisms helping to heal intestinal wounds.<\/li>\n<\/ul>\n
While we encourage synergy across disciplines, we recognize that ongoing uncertainty and logistical challenges continue to hinder collaboration. Research labs are contending with their unique local and institutional conditions. For many labs, the primary focus is on simply regaining momentum.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”20px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
\n“The generous support from the Rainin Foundation will enable us to boldly pursue mechanisms underlying inflammation in monogenic IBD that will provide new basic and translational insights directly from patients.”<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Carrie Lucas, PhD” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
\u2014Carrie Lucas, PhD<\/strong>, Yale University<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Symposium.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Photo credit: Kenneth Rainin Foundation<\/p>\n
Our 2021 Innovations Symposium convened online, allowing more people than ever to participate virtually and hear from experts working across disciplines.<\/h5>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Collaborating To Strengthen The Field” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Collaborating To Strengthen The Field<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”3.27.4″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Collaboration is a central tenet of the Rainin Foundation\u2019s values<\/a>. We believe that working in partnership and with a common purpose are essential to achieving our mission. In 2021, we joined a funding consortium with Foundation for the National Institutes of Health<\/a> and other industry and academic partners. Our aim is to address the need for standardized biomarkers for measuring mucosal healing in clinical trials for ulcerative colitis. Establishing standardized definitions allows for uniform protocols to reliably measure progress toward that treatment goal.<\/p>\nThe Rainin Foundation\u2019s annual Innovations Symposium is our cornerstone platform for sharing ideas and progress about research into IBD. Our 2021 Innovations Symposium<\/strong><\/a> convened online and engaged our largest-ever audience. Well over 400 people tuned in to hear from experts across multiple disciplines. More than 60% of attendees were students, post-docs and early career researchers, a cohort that is essential to advancing the field yet often unable to travel to conferences to learn and network. Dozens of industry, government and funding stakeholders also participated. The event showcased research and elevated the voices of people living with IBD. Foundation CEO Jen Rainin, Board member Dash Patterson and researcher Dr. Katie Pollard<\/a> reflected on their personal experiences with the disease and its impact on their families.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”20px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
\n“As a medical school student who was diagnosed with UC [ulcerative colitis] in 2015, this [symposium] was really motivating and interesting\u2026I am excited to see where the future of medicine goes in treating individuals with IBD.”<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px|30px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Jonathan Derouen” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
\u2014Jonathan Derouen<\/strong>, University of Oklahoma Health Sciences Center<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Ali.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Photo courtesy of Cedars-Sinai<\/p>\n
At Cedars-Sinai, Ali Rezaie, MD, is developing a novel technology using UVA light to help resolve inflammation.<\/h5>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Promising Ideas Gain Traction” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Promising Ideas Gain Traction<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”3.27.4″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
The Rainin Foundation is not afraid of being the first funder to support researchers with promising but untested ideas. Our grantees achieved important progress on an array of research that advances our understanding of IBD and improves quality of life for those living with the disease.<\/p>\n
One of those early investments supported Dr. Ilian Iliev\u2019s<\/a> investigations into the fungal microbiome\u2019s role in mucosal immunity and inflammation\u2014an area of study that has since gained scientific interest. Dr. Iliev\u2019s latest research, published in Nature Microbiology,<\/a> revealed that antibody protection against harmful forms of fungi in the gut may be disrupted in some patients with Crohn\u2019s disease.<\/p>\nOur early support also helped Dr. Ali Rezaie<\/a> at Cedars-Sinai develop novel technology using UVA light to help resolve inflammation. In 2021, we approved new funding to test a refined, miniaturized device in a human trial of patients with ulcerative proctitis. These patients are typically excluded from clinical trials to treat ulcerative colitis. This innovative intervention holds promise for improving the quality of life for people living with IBD.<\/p>\nOther grantee research also advanced. For example:<\/p>\n
\n- Heather Kaplan, MD, MSCE<\/strong><\/a>, Cincinnati Children’s Hospital, led a clinical study of pediatric patients with active IBD that showed dietary changes can reduce clinical symptoms and improve inflammatory burden. With more viable treatment options, patients and families can have greater autonomy in managing their disease.<\/li>\n
- Carla Rothlin, PhD<\/strong><\/a>, Yale School of Medicine, continued to investigate the molecular basis of the fibroblast response to a specific type of cell death called necroptosis, which appears to inhibit the healing action. Understanding the connection between necroptosis and fibroblast response could illuminate therapeutic vulnerabilities in IBD.<\/li>\n
- Kevin Whelan, PhD<\/strong><\/a>, King\u2019s College, led the first randomized control trial of the effects of a diet low in fermentable carbohydrates in patients with Crohn’s disease. Research encompassed the effect on persistent gut symptoms, the intestinal microbiome and circulating inflammation markers in patients with inactive IBD.<\/li>\n<\/ul>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_ResearchCollaboration.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Photo credit: Morsa Images, Getty Images<\/p>\n
The Rainin Foundation supports scientists to collaborate across disciplines on innovative research that could improve patients\u2019 lives.<\/h5>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Investing In Cross-Disciplinary Research: 2020 Grantees” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Breaking New Ground In IBD Research:
2021 Grantees<\/p>\n
[\/et_pb_text][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_5,3_5″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”invested $XX million” _builder_version=”3.27.4″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
The Rainin Foundation invested nearly $3.5 million in 2021 to support IBD research.<\/h2>\n
Health grantmaking supports groundbreaking ideas that have the potential to dramatically transform the prediction and prevention of Inflammatory Bowel Disease.<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”audit text” _builder_version=”3.27.4″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
Note: Grantmaking amount includes $.97 million of multi-year grants committed in a prior year. Financials are subject to audit verification.<\/em><\/p>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/HealthGrantmakingChart2021.png” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||122px||” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][et_pb_text admin_label=”Innovator Awards” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” hover_enabled=”0″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
INNOVATOR AWARDS<\/strong><\/p>\nGrants support an international pool of early-career and seasoned researchers to study untested ideas that could lead to breakthrough discoveries about IBD. Learn more about the 2021 Innovator Award grantees<\/strong><\/a>.<\/p>\n[\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
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\n\t\t\t\t\tGregory Barton, PhD, University of California, Berkeley<\/p>\nIsaac Chiu, PhD, Harvard Medical School<\/p>\n
Andrew Goodman, PhD, Yale University<\/p>\n
Carrie L. Lucas, PhD, Yale University<\/p>\n
Shruti Naik, PhD, and Daniel Rosenblum, PhD, New York University Grossman School of Medicine<\/p>\n\t\t\t\t<\/div>
\n\t\t\t\t\tFrancesca Petralia, PhD, Jean-Fr\u00e9d\u00e9ric Colombel, MD, and Zeynep Gumus, PhD, Icahn School of Medicine at Mount Sinai<\/p>\n
Eran Segal, PhD, Weizmann Institute of Science, and Nitsan Maharshak, PhD, Tel Aviv Sourasky Medical Center<\/p>\n
Anna Simon, PhD, and Fiona Powrie, PhD, University of Oxford<\/p>\n\t\t\t\t<\/div>
<\/div>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Synergy Awards” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\nSYNERGY AWARDS<\/strong><\/p>\nGrants support cross-disciplinary teams of researchers who are pursuing collaborative projects aimed at improving the prediction and prevention of IBD. The 2021 Synergy Awards cycle was put on hold. In 2022, we consolidated our\u00a0<\/span>Innovator<\/em>\u00a0Awards and\u00a0<\/span>Synergy<\/em>\u00a0Awards into one grant\u00a0<\/span>program\u2014the\u00a0<\/span>Innovator\u00a0Awards.<\/span><\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Special Initiatives” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
SPECIAL INITIATIVES<\/strong><\/p>\nThis invitation-only grant supports bold ideas that have the potential to lead to scientific breakthroughs for researchers and people living with Inflammatory Bowel Disease (IBD). Learn more about the Special Initiative grantees<\/strong><\/a>.<\/p>\n[\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
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\n\t\t\t\t\tAli Rezaie, MD, Cedars-Sinai\n\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t<\/div><\/div>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Explore” _builder_version=”3.27.4″ text_font=”Georgia||||” text_font_size=”20″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” custom_padding_last_edited=”on|phone” use_border_color=”off” border_color=”#ffffff” border_style=”solid” saved_tabs=”all” global_colors_info=”{}”]<\/p>\n\nExplore the Foundation\u2019s website to learn more about our Health program<\/a> and meet our\u00a0staff<\/a> and Board members<\/a>.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ z_index_tablet=”500″ global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Turning Points 2021″ module_class=”tpfoot” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n
<\/p>\n
Yet researchers continued working\u2014analyzing data, publishing papers<\/a> and troubleshooting technical challenges. They created new platforms for connecting and sharing expertise more widely, innovated new strategies in clinical studies and contributed to COVID-19 research and treatment.<\/p>\n To support our grantees, the Rainin Foundation stayed connected and listened carefully to what they needed. We looked for ways we could tailor financial and other supports that were sensitive to their distinct challenges. And we offered flexibility through no-cost extensions and top-up funding with minimal application requirements.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”10px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \n“As funders, it\u2019s imperative for us to continue to listen to our grantee community to understand the best ways to support them. Their students and trainees are especially vulnerable, yet essential to the future of science.”<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”||30px|50px” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Laura Wilson” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Laura Wilson, PhD<\/strong>, Director, Health Strategy & Ventures<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_HealthTejalDesai.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo courtesy of Tejal Desai<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Advancing Equity To Advance Science” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Advancing Equity To Advance Science<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”3.27.4″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \nThe Rainin Foundation\u2019s commitment to equity extends across our organization and includes a sustained process of internal learning. Our focus on gender parity in Health grantmaking continued with our 2021 Innovator Awards<\/a>. Four of the eight research teams that received funding are led by women. Our 2021 Innovations Symposium<\/a> featured gender parity in the presenting speakers, including academic and industry leaders who identify as women. We remain committed to elevating underrepresented researchers to address persistent gender bias and gaps that affect medical research.<\/p>\n To build more equitable programs and practices, we began collecting grantee demographic data with applications for our 2022 Innovator Awards. Our Health program staff also collaborated with our Scientific Advisory Board<\/a> to gain their insights and expertise. In September, we convened members to examine how we can contribute to advancing racial and gender equity in biomedical research. There was strong consensus on the overall need to focus earlier in the academic and research pipeline. We explored ways to target younger scientists of color who are aspiring to research positions during their graduate studies.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”30px||30px|” custom_padding=”30px|30px|30px|30px” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Celebrating A 2021 Nobel Laureate” _builder_version=”4.14.8″ text_font_size=”1em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” background_layout=”dark” module_alignment=”center” hover_enabled=”0″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n GRANTEE MILESTONE<\/p>\n Celebrating A 2021 Nobel Laureate<\/p>\n [\/et_pb_text][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Julius.jpg” url=”https:\/\/krfoundation.org\/rainin-foundation-celebrates-a-2021-nobel-laureate-among-its-health-grantees\/” url_new_window=”on” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ custom_margin=”||5px” z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”caption” _builder_version=”4.14.8″ text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark” custom_margin=”-10px||” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” custom_padding_last_edited=”on|phone” hover_enabled=”0″ z_index_tablet=”500″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n Photo credit: Noah Berger<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Improving Lives Through Novel Research” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Improving Lives Through Novel Research<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n The Rainin Foundation\u2019s Health grantmaking aims to improve the lives of IBD patients and to one day cure the disease. In May, we awarded $1.2 million through our Innovator Awards program, investing in early career and veteran IBD researchers alike. Grantees are pursuing a range of patient-focused ideas<\/a> with clinical implications from treating pain and inflammation to achieving lasting remission. Some highlights include:<\/p>\n While we encourage synergy across disciplines, we recognize that ongoing uncertainty and logistical challenges continue to hinder collaboration. Research labs are contending with their unique local and institutional conditions. For many labs, the primary focus is on simply regaining momentum.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”20px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \n“The generous support from the Rainin Foundation will enable us to boldly pursue mechanisms underlying inflammation in monogenic IBD that will provide new basic and translational insights directly from patients.”<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Carrie Lucas, PhD” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Carrie Lucas, PhD<\/strong>, Yale University<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Symposium.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo credit: Kenneth Rainin Foundation<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Collaborating To Strengthen The Field” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Collaborating To Strengthen The Field<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”3.27.4″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Collaboration is a central tenet of the Rainin Foundation\u2019s values<\/a>. We believe that working in partnership and with a common purpose are essential to achieving our mission. In 2021, we joined a funding consortium with Foundation for the National Institutes of Health<\/a> and other industry and academic partners. Our aim is to address the need for standardized biomarkers for measuring mucosal healing in clinical trials for ulcerative colitis. Establishing standardized definitions allows for uniform protocols to reliably measure progress toward that treatment goal.<\/p>\n The Rainin Foundation\u2019s annual Innovations Symposium is our cornerstone platform for sharing ideas and progress about research into IBD. Our 2021 Innovations Symposium<\/strong><\/a> convened online and engaged our largest-ever audience. Well over 400 people tuned in to hear from experts across multiple disciplines. More than 60% of attendees were students, post-docs and early career researchers, a cohort that is essential to advancing the field yet often unable to travel to conferences to learn and network. Dozens of industry, government and funding stakeholders also participated. The event showcased research and elevated the voices of people living with IBD. Foundation CEO Jen Rainin, Board member Dash Patterson and researcher Dr. Katie Pollard<\/a> reflected on their personal experiences with the disease and its impact on their families.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”20px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \n“As a medical school student who was diagnosed with UC [ulcerative colitis] in 2015, this [symposium] was really motivating and interesting\u2026I am excited to see where the future of medicine goes in treating individuals with IBD.”<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px|30px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Jonathan Derouen” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \u2014Jonathan Derouen<\/strong>, University of Oklahoma Health Sciences Center<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Ali.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo courtesy of Cedars-Sinai<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Promising Ideas Gain Traction” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Promising Ideas Gain Traction<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”3.27.4″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n The Rainin Foundation is not afraid of being the first funder to support researchers with promising but untested ideas. Our grantees achieved important progress on an array of research that advances our understanding of IBD and improves quality of life for those living with the disease.<\/p>\n One of those early investments supported Dr. Ilian Iliev\u2019s<\/a> investigations into the fungal microbiome\u2019s role in mucosal immunity and inflammation\u2014an area of study that has since gained scientific interest. Dr. Iliev\u2019s latest research, published in Nature Microbiology,<\/a> revealed that antibody protection against harmful forms of fungi in the gut may be disrupted in some patients with Crohn\u2019s disease.<\/p>\n Our early support also helped Dr. Ali Rezaie<\/a> at Cedars-Sinai develop novel technology using UVA light to help resolve inflammation. In 2021, we approved new funding to test a refined, miniaturized device in a human trial of patients with ulcerative proctitis. These patients are typically excluded from clinical trials to treat ulcerative colitis. This innovative intervention holds promise for improving the quality of life for people living with IBD.<\/p>\n Other grantee research also advanced. For example:<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_ResearchCollaboration.jpg” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”3.27.4″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”30px|70px|30px|70px” custom_padding_tablet=”20px||20px” custom_padding_phone=”20px|20px|20px|20px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”]<\/p>\n Photo credit: Morsa Images, Getty Images<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Investing In Cross-Disciplinary Research: 2020 Grantees” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Breaking New Ground In IBD Research: [\/et_pb_text][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_5,3_5″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”invested $XX million” _builder_version=”3.27.4″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Health grantmaking supports groundbreaking ideas that have the potential to dramatically transform the prediction and prevention of Inflammatory Bowel Disease.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”audit text” _builder_version=”3.27.4″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n Note: Grantmaking amount includes $.97 million of multi-year grants committed in a prior year. Financials are subject to audit verification.<\/em><\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/HealthGrantmakingChart2021.png” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”3.23″ z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||122px||” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][et_pb_text admin_label=”Innovator Awards” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” hover_enabled=”0″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n INNOVATOR AWARDS<\/strong><\/p>\n Grants support an international pool of early-career and seasoned researchers to study untested ideas that could lead to breakthrough discoveries about IBD. Learn more about the 2021 Innovator Award grantees<\/strong><\/a>.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \n Isaac Chiu, PhD, Harvard Medical School<\/p>\n Andrew Goodman, PhD, Yale University<\/p>\n Carrie L. Lucas, PhD, Yale University<\/p>\n Shruti Naik, PhD, and Daniel Rosenblum, PhD, New York University Grossman School of Medicine<\/p>\n\t\t\t\t<\/div> Francesca Petralia, PhD, Jean-Fr\u00e9d\u00e9ric Colombel, MD, and Zeynep Gumus, PhD, Icahn School of Medicine at Mount Sinai<\/p>\n Eran Segal, PhD, Weizmann Institute of Science, and Nitsan Maharshak, PhD, Tel Aviv Sourasky Medical Center<\/p>\n Anna Simon, PhD, and Fiona Powrie, PhD, University of Oxford<\/p>\n\t\t\t\t<\/div> SYNERGY AWARDS<\/strong><\/p>\n Grants support cross-disciplinary teams of researchers who are pursuing collaborative projects aimed at improving the prediction and prevention of IBD. The 2021 Synergy Awards cycle was put on hold. In 2022, we consolidated our\u00a0<\/span>Innovator<\/em>\u00a0Awards and\u00a0<\/span>Synergy<\/em>\u00a0Awards into one grant\u00a0<\/span>program\u2014the\u00a0<\/span>Innovator\u00a0Awards.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Special Initiatives” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n SPECIAL INITIATIVES<\/strong><\/p>\n This invitation-only grant supports bold ideas that have the potential to lead to scientific breakthroughs for researchers and people living with Inflammatory Bowel Disease (IBD). Learn more about the Special Initiative grantees<\/strong><\/a>.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n \n \nExplore the Foundation\u2019s website to learn more about our Health program<\/a> and meet our\u00a0staff<\/a> and Board members<\/a>.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ z_index_tablet=”500″ global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Turning Points 2021″ module_class=”tpfoot” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]<\/p>\n <\/p>\nTejal Desai, PhD, brings valuable expertise and leadership to our Scientific Advisory Board and is an influential voice in science. With her bioengineering co-authors, Dr. Desai published a strong call for racial equity in federal funding in Cell<\/u><\/a>.<\/u><\/h5>\n
Dr. David Julius, professor and chair of the Department of Physiology and the Morris Herzstein Chair in Molecular Biology and Medicine at University of California, San Francisco, was awarded the 2021 Nobel Prize<\/u><\/a> for his research into the molecular basis for the sensations of pain and pressure. He received the prize jointly with Ardem Patapoutian, PhD, a molecular biologist at Scripps Research. Dr. Julius\u2019 groundbreaking work has significant implications for people living with IBD.<\/h5>\n
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Our 2021 Innovations Symposium convened online, allowing more people than ever to participate virtually and hear from experts working across disciplines.<\/h5>\n
At Cedars-Sinai, Ali Rezaie, MD, is developing a novel technology using UVA light to help resolve inflammation.<\/h5>\n
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The Rainin Foundation supports scientists to collaborate across disciplines on innovative research that could improve patients\u2019 lives.<\/h5>\n
2021 Grantees<\/p>\nThe Rainin Foundation invested nearly $3.5 million in 2021 to support IBD research.<\/h2>\n
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