Photo credit: Luis Alvarez, Getty Images<\/p>\n
Advancing Novel Research Insights<\/strong><\/p>[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] The Kenneth Rainin Foundation envisions a world where no one suffers from Inflammatory Bowel Disease (IBD). In 2023, our grantees\u2019 novel insights and cutting-edge technologies advanced the understanding and treatment of these diseases. Their innovations are identifying new targets for therapeutics and helping to speed the development of new drugs for those living with IBD. Throughout the year, we remained focused on advancing equity in our practices and promoting greater diversity in the field to improve outcomes for patients.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”10px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u201cAt the heart of our commitment to finding a cure for IBD is a focus on advancing novel research, fostering collaborations and embracing diverse perspectives.\u201d<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”33px” custom_margin=”|auto|31px|auto||” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Shelley Trott” module_class=”quotee” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u2014Shelley Trott<\/strong>, Chief Program Officer<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”702.1px” custom_margin=”-11px|auto||auto||” custom_padding=”||0px|” hover_enabled=”0″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}” sticky_enabled=”0″ min_height_last_edited=”on|phone” min_height_phone=”” min_height_tablet=”702.1px”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_getty2.jpg” alt=”A group of hospital workers wearing wearing medical masks and uniforms stand looking at the camera.” title_text=”1080-575_Health_getty2″ align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.14.8″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”4.14.8″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”5px|70px|30px|70px|false|false” custom_padding_tablet=”5px||20px||false|false” custom_padding_phone=”5px|20px|20px|20px|false|false” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”] Photo credit: Fly View Productions, Getty Images<\/p>\n \u00a0Addressing Disparities In Research And Healthcare<\/strong><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”399.4px” custom_margin=”0px||||false|false” custom_padding=”0px|120px||120px|false|false” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|0px||” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] The lack of racial representation in healthcare and biomedical research negatively affects patients of color. Over the past few years, we have been building relationships with historically underrepresented researchers and research institutions to advance meaningful change. This work introduced us to two recently established organizations\u2014led by and for people of color\u2014that are at the forefront of addressing disparities for researchers, clinicians and patients of color.<\/p>\n The Association for Black Gastroenterologists and Hepatologists<\/a> (ABGH) promotes health equity in Black communities, advances science and develops the careers of Black clinicians and scientists. Our funding supported organizational capacity building and ABGH Rising, a new mentorship program that offers educational and career development workshops and pairs Black clinicians with Black medical students and trainees.<\/p>\n Color of Gastrointestinal Illnesses<\/a> promotes research, education and advocacy to improve the quality of life for people of color living with IBD and other chronic illnesses. Our grant funded communications and programming for patient education and awareness during IBD Awareness Week, in collaboration with ABGH. These investments reflect our commitment to improving patient outcomes, and to funding the people and ideas driving long-lasting change.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”10px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u201cSupporting the next generation of gastroenterologists through mentorship is invaluable, and the impact is readily evident as our participants become more competitive applicants and see themselves reflected through our leadership.\u201d<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”33px” custom_margin=”|auto|31px|auto||” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Shelley Trott” module_class=”quotee” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u2014Sophie Balzora<\/strong>, MD, FACG, President and Co-Founder, The Association of Black Gastroenterologists and Hepatologists (ABGH)<\/span><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Symposium_Panel.jpg” alt=”Fourt people are seated in chairs on a stage looking toward a person in the middle of them who is smiling and holding a microphone.” title_text=”1080-575_Health_Symposium_Panel” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.14.8″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”4.14.8″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”5px|70px|30px|70px|false|true” custom_padding_tablet=”5px||20px||false|false” custom_padding_phone=”5px|20px|20px|20px|false|false” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”] Photo credit: Mitch Tobias<\/p>\n Understanding Immunity And Inflammation<\/strong><\/p>[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] Our early funding for innovative ideas is leading to improvements in preventing, diagnosing and treating IBD. Grantees are unlocking new therapeutic targets by exploring unique aspects of the complex relationship between immunity and inflammation in health and disease.<\/p>\n “Rainin Foundation grantees are leading innovative research and collaborating across disciplines to advance the understanding of this complex disease.<\/em>\u201d<\/span><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”||30px|auto|false|false” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Laura Wilson” module_class=”quotee” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u2014Laura Wilson, PhD<\/strong>, Director, Health Strategy & Ventures<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.14.8″ background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”47px|auto|42px|auto||” custom_padding=”30px|30px|16px|30px|false|false” hover_enabled=”0″ z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;” global_colors_info=”{}” min_height_last_edited=”on|phone” sticky_enabled=”0″ custom_padding_last_edited=”on|phone” custom_padding_tablet=”30px|30px|16px|30px|false|false” custom_padding_phone=”30px|30px|16px|30px|false|false”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Placing Patients At The Heart Of A Technology Mission” _builder_version=”4.14.8″ text_font_size=”1em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” background_layout=”dark” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] BRINGING SCIENCE CLOSER TO THE PATIENT<\/p>\n Meet Dr. Scott Snapper<\/a><\/p>[\/et_pb_text][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Snapper.jpg” alt=”Dr. Scott Snapper in a white lab coat with his arms crossed, proudly smiling at camera. In the background is shelving filled with lab supplies.” title_text=”1080-575_Health_Snapper” url=”https:\/\/krfoundation.org\/news\/health\/meet-scott-snapper-scientific-advisory-board-co-chair\/%20″ url_new_window=”on” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.14.8″ custom_margin=”||5px” z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”caption” _builder_version=”4.14.8″ text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark” custom_margin=”-10px||” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”] Photo courtesy of Scott Snapper.<\/p>\n Harnessing Interactions In The Microbiome <\/strong><\/p>[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] Many of our 2023 Innovator Award grantees<\/a> seek to harness metabolic interactions in the microbiome as promising avenues for new treatments. The field\u2019s increased focus on metabolites is leading to greater momentum in drug development and clinical testing. Momentum matters to patients.<\/p>\n “This funding will help my lab to understand new ways by which beneficial and harmful bacteria interact with B cells in the gut, which could have important implications for future treatment of IBD<\/em>.\u201d<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px||50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Anand Navalgund, PhD” module_class=”quotee” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u2014Manuela Raffatellu, MD<\/strong>, University of California, San Diego<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Spangler.jpg” alt=”two people in a medical lab setting lean onto a lab countertop and look at a white board.” title_text=”1080-575_Health_Spangler” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.14.8″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”4.14.8″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px||15px|||” custom_padding=”5px|70px|30px|70px|false|false” custom_padding_tablet=”5px||20px||false|false” custom_padding_phone=”5px|20px|20px|20px|false|false” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”] Photo courtesy of Johns Hopkins Biomedical Engineering.<\/p>\n Leveraging Advanced Technologies <\/strong><\/p>[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] Grantees are also leveraging advanced technologies and analytical methods in IBD research. Projects relate to regulating immune response, preventing disease progression and deciphering IBD\u2019s predictive factors.<\/p>\n Photo credit: Mitch Tobias<\/p>\n\n Rejuvenating Our In-Person Symposium<\/strong><\/p>[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] In July, an energized group of researchers and clinicians<\/a> attended the Rainin Foundation\u2019s first in-person Innovations Symposium since 2019. Speakers ranged from seasoned investigators to early- and mid-career innovators across various fields. Their presentations included the microbiome\u2019s role in maintaining homeostasis and contributing to inflammation, intriguing immunological connections to skin bacteria and the effect of circadian rhythms.<\/p>\n Our Innovations Symposium is a key strategy in our work to support early-career scientists. This event is designed to provide these investigators with opportunities to network and learn from leaders in the field. More than one-third of attendees were graduate students and postdocs, many of whom presented posters and benefited from our travel awards. In keeping with our long tradition of investing in the researcher pipeline, this year we doubled the number of those travel awards due to a record number of abstract submissions.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”20px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] “It was incredibly rewarding to share space in person again at the Innovations Symposium, and to combine outstanding presentations and panel discussions with ample time for networking and exchanging ideas one-on-one.\u201d<\/em><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”74px” custom_padding=”0px|50px|0px|50px||” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Shruti Naik” module_class=”quotee” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u2014Laura Wilson<\/strong>, Director, Health Strategy & Ventures<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ min_height=”796.3px” transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.14.8″ background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”813.3px” custom_margin=”30px||30px|” custom_padding=”30px|30px|30px|30px” hover_enabled=”0″ z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;” global_colors_info=”{}” min_height_last_edited=”on|phone” min_height_phone=”” sticky_enabled=”0″ min_height_tablet=”813.3px”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Placing Patients At The Heart Of A Technology Mission” _builder_version=”4.14.8″ text_font_size=”1em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” background_layout=”dark” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] CELEBRATING A MILESTONE<\/p>\n Honoring Dr. Averil Ma\u2019s Enduring Legacy<\/a><\/p>[\/et_pb_text][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_AverilMa.jpg” alt=”Two people smile and stand closely, while posing for camera. The person on the right holds a wooden and black plaque with metallic lettering” title_text=”1080-575_Health_AverilMa” url=”https:\/\/krfoundation.org\/news\/health\/honoring-dr-averil-mas-enduring-legacy-on-our-health-program\/%20″ url_new_window=”on” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.14.8″ custom_margin=”||5px” z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”caption” _builder_version=”4.14.8″ text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_layout=”dark” custom_margin=”-10px||” custom_padding=”0px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”] Photo credit: Mitch Tobias<\/p>\n Collaborating To Advance Science And Equity<\/strong><\/p>[\/et_pb_text][et_pb_text admin_label=”Copy” _builder_version=”4.14.8″ header_text_color=”#006666″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]The Rainin Foundation is part of the Foundation for the National Institutes of Health\u2019s Biomarkers Consortium on Mucosal Healing in Ulcerative Colitis<\/a>. This initiative brings together clinicians, academics, industry and funders to standardize a definition of mucosal healing and the protocols for measuring it. This work has the potential to improve disease assessment, treatment and patient outcomes and to facilitate drug development. In 2023, the Consortium published clinical research findings<\/a> and an analysis of biopsy protocol survey results. Consortium members also began pilot testing machine learning methods and its ability to replicate or outperform existing histological scoring systems.\n\nWe continue to participate in the Open and Equitable Funding Model Program<\/a> with other biomedical research funders<\/span>. Our collective aim is to make funding practices, peer review processes and the resulting research outputs more transparent, inclusive and equitable. This year, we offered implicit bias training resources to our peer reviewers to help counter stereotyping and bias in decision-making. Collaborations like these play a vital role in our vision to transform the prediction and prevention of IBD.[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”20px|50px|0px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quote” module_class=”quote” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] “It\u2019s important to go into every grant application as an open slate and leave our biases behind and have scholarly debate among the reviewers. And something that I feel strongly about is identifying a diverse talent pool outside of the standard white male bias.\u201d<\/em><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”0px|50px|30px|50px” custom_padding_tablet=”|20px||20px” custom_padding_phone=”|0px||0px” z_index_tablet=”500″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Quotee – Shruti Naik” module_class=”quotee” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] \u2014Dr. Scott Snapper, <\/strong>Rainin Foundation Scientific Advisory Board Co-Chair as quoted in our blog “Meet Scott Snapper.”<\/u><\/a><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/1080-575_Health_Symposium_Reception.jpg” alt=”two people in business attire smile at the camera in the background are windows opening onto greenery” title_text=”1080-575_Health_Symposium_Reception” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.14.8″ z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”photo credit” _builder_version=”4.14.8″ text_font=”Arial||||” text_text_color=”#ffffff” text_font_size=”0.8em” text_line_height=”3em” header_5_font_size=”15px” header_5_line_height=”1.6em” background_color=”#336699″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” background_layout=”dark” custom_margin=”-60px|||” custom_padding=”5px|70px|30px|70px|false|false” custom_padding_tablet=”5px||20px||false|false” custom_padding_phone=”5px|20px|20px|20px|false|false” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ custom_css_main_element=”border-radius: 20px;||z-index: 1000;” use_border_color=”off” global_colors_info=”{}”] Photo credit: Mitch Tobias<\/p>\n Fueling Advances In IBD Research<\/strong>: Health grantmaking supports groundbreaking ideas that have the potential to dramatically transform the prediction and prevention of Inflammatory Bowel Disease.<\/p>[\/et_pb_text][et_pb_text admin_label=”audit text” _builder_version=”3.27.4″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] Note: Financials are subject to audit verification.<\/em><\/p>[\/et_pb_text][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/krfoundation.org\/year-in-review\/wp-content\/uploads\/sites\/2\/Health2023Financials.gif” alt=”pie chart shows .73 million in program-related expenses and 4.7 million in grantmaking” title_text=”Health2023Financials” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.14.8″ z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][et_pb_text admin_label=”Innovator Awards” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] INNOVATOR AWARDS<\/strong><\/p>\n Grants support an international pool of early-career and seasoned researchers to study untested ideas that could lead to breakthrough discoveries about IBD. Learn more about the\u00a02023 Innovator Award grantees.<\/strong><\/a><\/p>[\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] INNOVATOR AWARDS\u00a0\u2013 CONTINUED SUPPORT<\/strong><\/p>\n Grants support an international pool of early-career and seasoned researchers to study untested ideas that could lead to breakthrough discoveries about IBD. Research teams who demonstrate significant progress toward their original goals are eligible for up to two years of additional support. Learn more about the\u00a02023 Innovator Award grantees.<\/strong><\/a><\/p>[\/et_pb_text][et_pb_text admin_label=”Grantees” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”||0px|||” custom_padding_tablet=”” custom_padding_phone=”” custom_padding_last_edited=”on|phone” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”] COMPLEMENTARY GRANTMAKING<\/strong><\/p>\n This invitation-only grant supports bold ideas that have the potential to lead to scientific breakthroughs for researchers and people living with Inflammatory Bowel Disease (IBD).\u00a0<\/span> RESPONSE FUND<\/strong><\/p>\n This discretionary fund supports exceptional and emerging opportunities that will have an outsized impact and move us closer toward our vision of no one suffering from Inflammatory Bowel Disease, Bay Area artists thriving and all Oakland children reading at or above grade level. \nExplore the Foundation\u2019s website to learn more about our Health program<\/a> and meet our staff and Board members<\/a>.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.2″ z_index_tablet=”500″ global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Turning Points 2022″ module_class=”tpfoot” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]Diverse perspectives are crucial to advancing science and improving outcomes for patients.<\/h5>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”-11px|auto||auto||” custom_padding=”|75px||75px|false|false” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” hover_enabled=”0″ make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}” sticky_enabled=”0″][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Adapting To An Evolving Landscape ” module_class=”header health” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” custom_padding=”|||0px||” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]
Immunologist Dr. Meghan Koch discusses her lab\u2019s research on maternal-fetal interactions during the Innovations Symposium.<\/h5>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”420.6px” custom_margin=”10px|auto||auto||” custom_padding=”|120px|20px|120px||” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Investigating Complex IBD Puzzles ” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” min_height=”31.2px” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]
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The Foundation\u2019s Scientific Advisory Board ensures a variety of perspectives and experiences guide our funding recommendations and strategies toward curing IBD. As the Board\u2019s Co-Chair, Dr. Snapper represents our priority of bringing science closer to the patient<\/a><\/span>.<\/h5>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”-26px|auto||auto||” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Leading Edge Research Builds Momentum” module_class=”header health” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]
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Dr. Jamie Spangler (left) uses innovative technologies in her lab to inform drug development.<\/h5>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” min_height=”524.9px” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Connecting Innovators And Diverse Research Perspectives” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” min_height=”47.2px” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]
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Dr. Fiona Powrie learns about Dr. Mohammad Arifuzzaman\u2019s research during the Innovations Symposium\u2019s poster sessions. <\/h5>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Fostering Equity in Biomedical Research” module_class=”header health” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” width=”100%” module_alignment=”center” custom_margin=”|18px||12px|false|false” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]
Averil Ma, MD, has been a scientific advisor to the Rainin Foundation for nearly two decades. At our Innovations Symposium, CEO Jen Rainin, PhD, celebrated his legacy of insight, guidance and unwavering advocacy<\/a><\/span> for early stage research and translational science.<\/h5>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22″ transparent_background=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”-21px|auto||auto||” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Fostering Equity in Biomedical Research” module_class=”header health” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]
Grantees Dr. Carrie Lucas, Yale University, and Dr. Xu Zhou, Boston Children\u2019s Hospital, at our Innovations Symposium.<\/h5>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|desktop” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Investing In Innovators: 2022 Grantees” module_class=”header health” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” module_alignment=”center” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]
2023 Grantees<\/p>[\/et_pb_text][et_pb_divider color=”#aec1cd” _builder_version=”3.19.9″ global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_5,3_5″ custom_padding_last_edited=”on|desktop” _builder_version=”4.14.8″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|120px||120px” custom_padding_tablet=”|50px||50px” custom_padding_phone=”|0px||0px” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”invested $XX million” _builder_version=”4.14.8″ header_text_color=”#336699″ header_2_text_color=”#336699″ header_2_line_height=”1.2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” z_index_tablet=”500″ use_border_color=”off” global_colors_info=”{}”]The Rainin Foundation invested over $5.4 million in 2023 to support IBD research.<\/h2>\n
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