Patients with Inflammatory Bowel Disease (IBD) have dysfunctions in gut motility, the movement of muscles in the gastrointestinal tract. Currently, most available therapeutics developed to directly target the gut fail to stabilize symptoms, suggesting that dysfunctions in gut motility could arise from pathological changes occurring outside the gut. Intriguingly, gut motility problems also occur at […]
Knowledge of the intestinal microbiota has transformed medical science, but not the treatment of Inflammatory Bowel Disease (IBD). The microbiota is difficult to use clinically because current analytical methods provide outputs that are too complex to provide useful data during an acute IBD flare. To solve these issues, we have developed a novel methodology, “MicFly,” […]
The bacteria in the human colon can influence gastrointestinal lining cells (intestinal epithelial cells (IECs)) and immune cells within the intestines and throughout the body. One way that bacteria do this is through their metabolites, the chemicals they produce. By influencing IECs and immune cells, gut bacterial metabolites affect resistance and susceptibility to Inflammatory Bowel […]
Inappropriate and chronic inflammatory responses underly the development of Inflammatory Bowel Diseases (IBD), including both ulcerative colitis and Crohn’s disease. This process is an intertwined, inter-cellular cascade among diverse immune cells and tissue stroma. The interactions between immune and stromal cells not only propagate inflammatory responses but also regulate resolution of inflammation. Yet, we do […]
Shotgun Players is a company of artists determined to create bold, relevant, affordable theatre that inspires and challenges audience and artist alike to re-examine our lives, our community and the ever-changing world around us.
Theatre Bay Area is dedicated to promoting the arts for all, embodying values of community, inclusion and service while advocating for diversity, equity and inclusion. As the largest arts service organization of its kind, Theatre Bay Area provides extensive resources to support its members’ radical creativity, contributing to the vibrant cultural landscape of the region.
A three-year capacity building grant of $150,000 to support the organizationÕs audience development strategies, community engagement efforts and marketing activities.
A three-year capacity building grant of $105,000 toÊincrease staff capacity for pursuing national opportunities, grow revenue to support an increased number of projects and increase local and national visibility to widen the pool of work opportunities.
A three-year capacity building grant of $150,000 toÊexplore new models for presenting and exhibiting, to develop a back office support system for small arts organizations and to continue to create greater efficiencies in their systems.
A three-year capacity building grant of $150,000 to support restructuring staff roles, expanding individual giving and building artistic infrastructure.