The Yilmaz lab seeks to understand how adult stem cells and their microenvironment adapt to diverse diets in the context of tissue regeneration, aging and cancer initiation.
The Walz laboratory uses molecular electron microscopy to study macromolecular complexes and membrane proteins in a lipid environment. Their research focuses on membrane proteins and biological membrane-related processes, such as vesicular transport.
The Sumagin lab is exploring the roles of innate immune cells in regulating intestinal homeostasis, wound healing, host pathogen interactions and cancer development. They are using various approaches to study leukocyte trafficking in mucosal tissues.
Dr. Steller’s research focuses on how programmed cell death is regulated and how its dysfunction contributes to disease. They also study the nonlethal use of cell death proteins for cellular remodeling, and protein degradation in development, aging and disease.
The Scharschmidt lab investigates the cellular and molecular mechanisms that mediate interactions between bacteria and the developing immune system, with a long-term goal of developing new therapeutic approaches.
Dr. Rosen’s research focuses on how the immune system and cellular metabolism regulate epithelial function in IBD. His clinical research focuses on optimization of biologic therapy in pediatric IBD, particularly acute severe ulcerative colitis.
The Rieder lab focuses on the discovery of novel mechanisms of intestinal fibrogenesis, the prediction of fibrostenosing disease courses and innovative ways to treat Inflammatory Bowel Disease patients with established strictures.
The Petralia lab focuses on developing novel computational methods for the integration of high-dimensional omic data to enhance the understanding of complex diseases.
The Nice lab studies the biology of the intestinal innate immune cells and cytokines—how they promote intestinal health and resistance to infection. They seek to understand how immune pathways function and become dysfunctional in disease states.
The Murphy lab is focused on understanding how proteins within cells, specifically those involved in cell signaling, interact and how genetic mutations that perturb these interactions can cause disease.
