Dr. Kayal specializes in the care of patients with gastrointestinal illnesses with a focus on ulcerative colitis and Crohn’s disease. Her current research interests include prediction and risk stratification in ulcerative colitis patients who need surgery.
Dr. Kamada’s lab investigates how gut microbiota and host immunity interact in gastrointestinal health and disease. Their focus is on the mechanism by which certain pathogenic members of commensal bacteria promote chronic intestinal inflammation that leads to Inflammatory Bowel Disease.
The Iliev lab studies the mechanisms by which fungal and bacterial symbionts interact with their host to influence immunity and homeostasis, or contribute to intestinal diseases, allergies and cancers.
The Hang lab aims to understand the chemical mechanisms that modulate host-microbe interactions and translate discoveries into new therapeutic approaches.
The Hand lab is interested in the immune cells of the intestine and how they respond to the first interactions with colonizing microorganisms. Too little immune response can lead to infection but too much can contribute to damaging inflammation.
Using genetic approaches, the Guo lab seeks to understand and reprogram the molecular “language” of host-microbe interactions in health and disease for potential therapeutic applications.
The Goodman lab aims to dissect the mechanisms that commensal gut microbes use to compete, cooperate and antagonize each other in the gut and explore how microbiome variation impacts our response to pathogenic infection and medical drugs.
The Garrett lab focuses on mucosal immunology and the gut microbiota. They study intestinal inflammation in colitis and the tumor microenviroment in colorectal cancer, with a specific focus on the gut microbiota and immune system.
Dr. Alenghat’s lab investigates cell homeostasis in intestinal health and disease, searching for insight into pathways that mediate the host-microbiota relationship and how regulation affects innate immunity and chronic conditions like IBD.
Dr. Elson’s lab focuses on the regulation of mucosal immune responses, particularly the mucosal immune response to the microbiota, to define the cellular and molecular mechanisms that maintain mucosal immune homeostasis.
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