The Rainin Foundation believes that partnerships and collaborations allow for the biggest impact in research. We invest in bold ideas and initiatives that have the potential to lead to scientific breakthroughs for researchers and people living with Inflammatory Bowel Disease (IBD).


GutCheck consists of wearable patches that non-invasively detect electrical signals produced by the smooth muscles of the stomach, small intestine and colon. Data are transmitted to a smart phone and relayed to G-Tech Medical for analyses and reporting.

Monitoring Gut Motility

In December 2016, the Rainin Foundation’s Health Program awarded its first grant to a biotech start-up. G-Tech Medical was granted $250,000 to continue development of GutCheck, a medical device that could transform how gastrointestinal motility is monitored. Funding from the Rainin Foundation will allow for further algorithm development and a small study to examine the efficacy and reproducibility of data collected using GutCheck.

Microbial Restoration for IBD

The Rainin Foundation has awarded researchers at the University of California, San Francisco $946,000 to investigate fecal microbial transplantation (FMT) as a mechanism for restoring microbial health in patients with IBD. The study, led by Dr. Najwa El-Nachef and in collaboration with Openbiome, will focus on understanding how the mode of delivery impacts engraftment – the successful establishment of transplanted microbial populations, in patients with ulcerative colitis.



These reports and guides extend our grantmaking impact and advance our mission in complementary ways.

The Rainin Foundation joined forces with OpenBiome to explore Fecal Microbiota Transplantation (FMT) as a potentially transformative therapy for IBD. This report provides:

  • an overview of the current state of the field
  • insights on the promise of FMT for IBD

View the report.

We partnered with the Philanthropy Advisory Service of the Milken Institute to learn how strategic philanthropic investments can change the trajectory of IBD research. A Giving Smarter Guide includes:

  • the current state of research and promising directions
  • research barriers and critical funding gaps
  • potential solutions for addressing challenges

View the guide.

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