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Abstract or Project Description

Abstract or Project Description

Expands families’ capacity to support literacy development.

Abstract or Project Description

The Rest and Care Award is a one-time, invite-only program for current and past Education and Arts nonprofit grantees, offering six-week sabbaticals with pro-rated salary, benefits, leave expenses and organizational support, recognizing the dedication and resilience of leaders in our grantee community. Lead Liberated is an Oakland-based nonprofit that equips education leaders with the tools to interrupt racism within themselves and co-design antiracist cultures within their schools. Their Executive Director of three years is Daneen Keaton.

Abstract or Project Description

Provides support for anti-racist coaching and training for educators.

Abstract or Project Description

The Rest and Care Award is a one-time, invite-only program for current and past Education and Arts nonprofit grantees, offering six-week sabbaticals with pro-rated salary, benefits, leave expenses and organizational support, recognizing the dedication and resilience of leaders in our grantee community. Lenora Lee Dance creates and presents large-scale multimedia and immersive performance works integrating dance, original music, video projection and text. Founder and Artistic Director Lenora Lee has led the organization for 16 years.

Abstract or Project Description

Provides TK-2 literacy coaching and training for educators in Lighthouse Community Schools.

Abstract or Project Description

The Rest and Care Award is a one-time, invite-only program for current and past Education and Arts nonprofit grantees, offering six-week sabbaticals with pro-rated salary, benefits, leave expenses and organizational support, recognizing the dedication and resilience of leaders in our grantee community. Lotus Bloom is a network of family resource centers that provides safe, welcoming and inclusive community spaces to traditionally underserved children in Oakland’s flatlands. Their founder and executive director for 15 years is Angela Louie Howard.

Abstract or Project Description

Provides early language and literacy development for children 0-5 and expands families’ capacity to support development.

Abstract or Project Description

Mabuhay Health Center (MHC) is a volunteer-run organization in San Francisco’s SoMa district, focusing on providing culturally sensitive healthcare to the elderly Filipino population, with services including a free community health clinic at the Bayanihan Community Center and tailored health education workshops for youth.

Abstract or Project Description

The Rest and Care Award is a one-time, invite-only program for current and past Education and Arts nonprofit grantees, offering six-week sabbaticals with pro-rated salary, benefits, leave expenses and organizational support, recognizing the dedication and resilience of leaders in our grantee community. Magic Theatre is a center for creating and performing new American plays dedicated to supporting and centering BIPOC artists and the community. Managing Director Kevin Nelson has led the organization for five years.

Abstract or Project Description

Patients with Inflammatory Bowel Disease (IBD) have dysfunctions in gut motility, the movement of muscles in the gastrointestinal tract. Currently, most available therapeutics developed to directly target the gut fail to stabilize symptoms, suggesting that dysfunctions in gut motility could arise from pathological changes occurring outside the gut. Intriguingly, gut motility problems also occur at high frequencies in patients with neurological disorders, including neurodegenerative, neurodevelopmental and neuropsychiatric diseases, associated with dysregulated neural activity in a specific region of the brain, the cerebral cortex. We propose that dysregulated neural activity in the cortex contributes to the emergence of gut dysfunction. We will test this hypothesis by first identifying specific regions in the cortex that are anatomically connected to the gut and then determining if modulating neural activity within these regions alters gut function. Additionally, we will use established mouse models of various neurological disorders and IBD to ask whether restoring homeostatic levels of neural activity to the cortex improves gut phenotypes. Our study will provide anatomical and functional evidence to support the concept that cortical modulations regulate gut motility. Furthermore, the insight gained from the study can lead to novel therapeutics for ameliorating gut motility symptoms in IBD patients.

Abstract or Project Description

Despite medical advances, a significant proportion of Inflammatory Bowel Disease (IBD) patients are resistant to therapies, with CD4 T cells being consistently activated. Analysis of inflamed tissues from a cohort of refractory IBD patients reveals an enrichment of metabolism gene transcripts in CD4 T cells. Exploring the mechanisms, our preliminary data demonstrate that several proinflammatory cytokines can independently trigger metabolic phenotypes which we believe reinvigorates the pathogenic function of CD4 T cells. This led us to formulate the hypothesis that IBD CD4 T cells, governed by metabolic cues, utilize common intracellular metabolites to drive inflammatory response that results in disease pathogenesis. Thus, our research goal is to identify the metabolic vulnerabilities of IBD CD4 T cells, which will consequently guide strategies for developing efficacious therapies.

Abstract or Project Description

Direct aid for Gaza, Palestine.

Abstract or Project Description

Expands access to research for diverse audiences through investigative journalism.

Abstract or Project Description

Patients with Inflammatory Bowel Disease (IBD) have dysfunctions in gut motility, the movement of muscles in the gastrointestinal tract. Currently, most available therapeutics developed to directly target the gut fail to stabilize symptoms, suggesting that dysfunctions in gut motility could arise from pathological changes occurring outside the gut. Intriguingly, gut motility problems also occur at high frequencies in patients with neurological disorders, including neurodegenerative, neurodevelopmental and neuropsychiatric diseases, associated with dysregulated neural activity in a specific region of the brain, the cerebral cortex. We propose that dysregulated neural activity in the cortex contributes to the emergence of gut dysfunction. We will test this hypothesis by first identifying specific regions in the cortex that are anatomically connected to the gut and then determining if modulating neural activity within these regions alters gut function. Additionally, we will use established mouse models of various neurological disorders and IBD to ask whether restoring homeostatic levels of neural activity to the cortex improves gut phenotypes. Our study will provide anatomical and functional evidence to support the concept that cortical modulations regulate gut motility. Furthermore, the insight gained from the study can lead to novel therapeutics for ameliorating gut motility symptoms in IBD patients.

Abstract or Project Description

Convenes literacy nonprofits and educators, as well as provides literacy advocacy and data-sharing.

Abstract or Project Description

The Rest and Care Award is a one-time, invite-only program for current and past Education and Arts nonprofit grantees, offering six-week sabbaticals with pro-rated salary, benefits, leave expenses and organizational support, recognizing the dedication and resilience of leaders in our grantee community. Oakland Literacy Coalition is a coordinating and capacity-building organization dedicated to improving literacy outcomes in Oakland. Their Founding Co-Executive Director of eight years is Sanam Jorjani.

Abstract or Project Description

Convenes early childhood organizations and educators, as well as provides early care advocacy and data-sharing.

Abstract or Project Description

Provides TK-2 literacy and language coaching and training for educators in OUSD focal schools.

Abstract or Project Description

The Rest and Care Award is a one-time, invite-only program for current and past Education and Arts nonprofit grantees, offering six-week sabbaticals with pro-rated salary, benefits, leave expenses and organizational support, recognizing the dedication and resilience of leaders in our grantee community. Parent Voices is a parent-led grassroots organization that advocates for affordable, accessible, quality childcare. Their Executive Director of 12 years is Clarissa Doutherd.