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Abstract or Project Description

Abstract or Project Description

To support safety improvements at St. Mary School.

Abstract or Project Description

To purchase furniture and fixtures.

Abstract or Project Description

Patients with inflammatory bowel diseases (IBD) can experience many years of inflammation and remission in the gastrointestinal tract. As a result, the intestines can undergo a structural change known as fibrosis, which narrows the inside. This narrowing is a major, and sometimes life-threatening, health issue for patients because it can block the passage of digested food and stool. Unfortunately, the only treatment for this condition consists of invasive surgical procedures to either widen the opening or remove the affected areas of the intestine. Therefore, there is an urgent need to develop less invasive therapies such as drug-based treatments. Preliminary studies carried out in our laboratory have pointed to a potential role for the molecule serine, an amino acid, in the development of intestinal fibrosis. For example, we have found that serine is produced in areas of fibrosis in the intestines of IBD patients and in our mouse model of intestinal fibrosis, suggesting that it may play a role in the development of this condition. The work proposed in this application will determine if in fact serine is largely responsible for intestinal fibrosis and establish methods to limit its production and thus prevent fibrosis development. Carrying out the proposed work can lead to the development of novel treatments for intestinal fibrosis and significantly improve the lives of patients with IBD.

Abstract or Project Description

Support for Bay Area programming.

Abstract or Project Description

Pieces of Home. In collaboration with Marina Fukushima, Surjit Nongmeikapam and Mercy Housing, this project will create an intergenerational and multi-disciplinary performance that engages questions of transforming and repurposing urban spaces for affordable housing in San Francisco’s Mission Bay neighborhood. The project takes place within context of Mission Bay’s history as both “terrain vague” (empty, abandoned, marginalized and ambiguous space) and the site of immense industrial, commercial and residential development. With the participation of residents of 691 China Basin apartment complex, the development phase will begin with outdoor environmental research and indoor movement workshops.

Abstract or Project Description

To continue its literacy programming in preschool and transitional kindergarten classrooms.

Abstract or Project Description

To support their community and school-based early learning programming in Oakland. In 2022-2023, Tandem aims to grow services in Oakland and provide high-quality early learning experiences for children ages birth to five. This includes adding new StoryCycles classrooms, deepening community-based early learning programs and offering families greater access to high quality books and materials.

Abstract or Project Description

In partnership with artists and the Oakland community, this project will illuminate, explore and celebrate the contributions of the Black Panther Party and African American community to Oakland’s Temescal neighborhood. This project’s development will begin with a series of community gatherings and conversations to elevate the voices of the Black Panther Party and Black business owners, residents, former residents and artists. Artist team-building workshops and collaboration events will build upon and help co-create the historical memory, cultural knowledge and public understanding of the Black Panther Party and Temescal’s identity and community.

Abstract or Project Description

Within the David Ireland House, this project will create a physical space to gather intergenerational stories, images and visual ephemera focused on trans joy and creative resilience. Primarily serving the trans Latinx community in San Francisco’s Mission district, the development process will include hosting weekly conversations with community organizations, artists and community members around trans self-representation, reaching out to the wider translatinx community and prototyping expansion into the production phase.

Abstract or Project Description

To support the East Bay Relief Fund for Individuals in the Arts.

Abstract or Project Description

Charlotte Maxwell Clinic is a 30-year-old nonprofit providing complementary, integrative therapies to low-income and underserved women with cancer.

Abstract or Project Description

To support the Deputy Director of Education role.

Abstract or Project Description

Curve magazine, launched in 1991 as Deneuve, has evolved into AmericaÕs leading lesbian magazine under the guidance of founder Franco Stevens. Ahead of its 30th anniversary, Franco reimagined Curve’s role, founding The Curve Foundation to empower and support the LGBTQ+ community through storytelling, leadership development and archival preservation, ensuring the continuity of LGBTQ+ women’s culture and history.

Abstract or Project Description

The PeopleÕs Conservatory empowers young artists, particularly from Black and Brown marginalized communities, to create meaningful art that addresses social issues, fostering cultural awareness and positive change. Through a curriculum rooted in ethnic and cultural studies, students develop their artistic voices and become leaders in their communities.

Abstract or Project Description

Abstract or Project Description

To continue educator retention and sustainability programs at seven elementary schools and within several leadership teams.

Abstract or Project Description

The Unquiet Professional is a organization committed to recognizing and honoring our nationÕs Gold Star & Surviving Families, Veterans and military families by providing rewarding and purposeful opportunities to heal from the wounds of war.

Abstract or Project Description

For general support and to provide support for the executive director transition.

Abstract or Project Description

The project will use mouse models of colitis to investigate the effects of TP-317 (Resolvin E1 magnesium lysinate) in blood, feces and intestinal tissue on key biomarkers that are involved in IBD pathophysiology and that Resolvin E1 has been shown to regulate in prior experiments. Key biomarkers of interest include (a) cytokines such as G-CSF, GM-CSF, IFN-γ, IL-10, IL-12p40, IL-12p70, IL-15, IL-17A, IL-8, IL-1β, IL-2, IL-23, IL-6, TGF-β1 and TNF-α; (b) intestinal alkaline phosphatase, a protein that plays a role in maintaining gut homeostasis and (c) Lipocalin-2 (LCN2), a marker of inflammation in feces. Unbiased RNA sequencing of tissue also will be conducted to identify novel biomarkers. Lastly, the study will evaluate the relationship between disease activity and biomarker response to identify potential biomarkers for clinical investigation.