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Abstract or Project Description

Abstract or Project Description

A new ensemble work instigated by Jess Curtis in collaboration with a diverse ensemble of Blind, Low Vision and sighted artists and consultants, which will examine cultural and phenomenological experiences of darkness and light. Into the Dark addresses the physical, subconscious and literal effects of Western thought’s binary mobilization of darkness and light in societal and individual creations of meaning.

Abstract or Project Description

Established in 1986 to support Joe Goode’s artistic endeavors, the Joe Goode Performance Group (JGPG) became a radical voice during the AIDS epidemic in San Francisco, blending text, gestures, humor and dance to promote connection and compassion. Recognized in 2019 as a Legacy Business for its history of centering the Queer experience, JGPG is celebrated for its innovative site-responsive installations and intimate theatrical performances.

Abstract or Project Description

Kara, the sole standalone grief-focused agency in the Bay Area, annually serves 4,000 individuals with crucial bereavement support services, providing comprehensive grief support, crisis intervention and education since 1976. Through accessible, research-based interventions in English and Spanish, Kara fosters resilience, prevents and alleviates advanced reactions to loss and trauma, contributing to the well-being of the community

Abstract or Project Description

KQED offers Northern Californians a community-supported media platform, providing informative content, fostering dialogue, promoting arts accessibility, facilitating storytelling and enhancing education for students and teachers while encouraging exploration for all ages.

Abstract or Project Description

“That’s My Word: The Influential, Underrecognized History of Bay Area Hip-Hop” is a documentary produced by KQED, exploring the significant yet often overlooked history of Bay Area hip-hop.

Abstract or Project Description

A new project commissioned by the Asian Art Museum that explores the talismanic power of dance through a multidisciplinary ritual performance. Over the next year, a series of workshops examining a cross section from the Museum’s collections will offer the rare opportunity to critically reassess the ways these pieces have been interpreted, renegotiate our relationships to the institution and explore how Pilipino Americans might build artistic tools to unravel the wounds of colonialism.

Abstract or Project Description

Support to provide high-quality services to people with intellectual and developmental disabilities in Contra Costa County.

Abstract or Project Description

To support Logan McWilliams in the development of instructional resources that honor African American Vernacular English (AAVE) as children learn Standard English.

Abstract or Project Description

To support the development of their three-year plan towards their mission of facilitating anti-racist training for cohorts of school instructional leaders. Leadership for Liberation is in the process of codifying their three-year program for principals to earn the clear administrative services credential. Leadership for Liberation aims to expand their current cohort of leaders and increase impact.

Abstract or Project Description

For a teacher-in-training position that designs an innovative educator pathway by braiding funding from multiple state grants.

Abstract or Project Description

To update their staffing model and add a new position called the Teacher in Training, who will serve as an instructional aide and tutor. Lighthouse aims to provide academic and relational continuity for students throughout the day and invest in staff career pathways.

Abstract or Project Description

For their capital campaign to establish the San Antonio Family Resource Center, which is a hub of research, training and knowledge sharing resources for the greater community. They aim to engage young learners and their caregivers in culturally relevant, responsive programming and parent leadership development.

Abstract or Project Description

A multidisciplinary, Black-centered no-holds-barred exploration of race and equity. The performance engages evolving legal policies, public sentiment and lived reality to consider how the boundaries and public perception of Black life are constructed and maintained and the ongoing effect of such policies.

Abstract or Project Description

The Luggage Store, also known as The 509 Cultural Center, is a nonprofit arts organization whose mission is to foster community through multidisciplinary arts programming that promotes diversity, inclusion and dialogue among the diverse cultural communities of downtown San Francisco. They aim to reduce inter-group tensions and stereotypes through exhibitions, performances, education and public art initiatives.

Abstract or Project Description

Patients with inflammatory bowel disease (IBD) have dysfunctions in gut motility (the movement of muscles in the gastrointestinal tract). Currently, most available therapeutics developed to directly target the gut fail to stabilize symptoms, suggesting that dysfunctions in gut motility could arise from pathological changes occurring outside the gut. Intriguingly, gut motility problems also occur at high frequencies in patients with neurological disorders, including neurodegenerative, neurodevelopmental and neuropsychiatric diseases, associated with dysregulated neural activity in a specific region of the brain—the cerebral cortex. We propose that dysregulated neural activity in the cortex contributes to the emergence of gut dysfunction. We will test this hypothesis by first identifying specific regions in the cortex that are anatomically connected to the gut and then determining if modulating neural activity within these regions alters gut function. Additionally, we will use established mouse models of various neurological disorders and IBD to ask whether restoring homeostatic levels of neural activity to the cortex improves gut phenotypes. Our study will provide anatomical and functional evidence to support the concept that cortical modulations regulate gut motility. Furthermore, the insight gained from the study can lead to novel therapeutics for ameliorating gut motility symptoms in IBD patients.

Abstract or Project Description

Despite medical advances, a significant proportion of inflammatory bowel disease (IBD) patients are resistant to therapies, with CD4 T cells being consistently activated. Analysis of inflamed tissues from a cohort of refractory IBD patients reveals an enrichment of metabolism gene transcripts in CD4 T cells. Exploring the mechanisms, our preliminary data demonstrate that several proinflammatory cytokines can independently trigger metabolic phenotypes which we believe reinvigorates the pathogenic function of CD4 T cells. This led us to formulate the hypothesis that IBD CD4 T cells, governed by metabolic cues, utilize common intracellular metabolites to drive inflammatory response that results in disease pathogenesis. Thus, our research goal is to identify the metabolic vulnerabilities of IBD CD4 T cells, which will consequently guide strategies for developing efficacious therapies.

Abstract or Project Description

In IBD, the microbes within the intestinal tract, collectively known as the microbiota, are targeted by inappropriate immune responses. There are also a number of changes in the microbiota composition that are thought to drive or amplify IBD pathology. One of these is the expansion of E. coli. However, our preliminary data has identified select E. coli isolates that limit intestinal pathology in mouse models of colitis by activating intestinal macrophages that either limit inflammation or promote barrier repair, two therapeutic endpoints for IBD. These results indicate that while some E. coli may amplify disease, others may protect against it. Understanding these differences will allow us to develop novel therapeutics.

Abstract or Project Description

To support academic programs and staffing at Menlo-Atherton High School.

Abstract or Project Description

To support general operations and research.