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Abstract or Project Description

Abstract or Project Description

Established in 1986 to support Joe Goode’s artistic endeavors, the Joe Goode Performance Group (JGPG) became a radical voice during the AIDS epidemic in San Francisco, blending text, gestures, humor and dance to promote connection and compassion. Recognized in 2019 as a Legacy Business for its history of centering the Queer experience, JGPG is celebrated for its innovative site-responsive installations and intimate theatrical performances.

Abstract or Project Description

The interleukin-2 (IL-2) protein plays an essential role in regulating the immune response and preventing the development of autoimmune disorders by supporting the growth and activity of regulatory T cells (Tregs). Promising preclinical and clinical work has demonstrated the potential for IL-2 to mitigate autoimmune diseases, including Inflammatory Bowel Disease (IBD). However, in addition to stimulating Tregs, IL-2 also stimulates effector T cells and natural killer (NK) cells, which drive inflammation and lead to autoimmune disease progression. Thus, developing a biased version of IL-2 that activates Tregs but not effector T or NK cells would represent a monumental advance for autoimmune disease therapy. A recently discovered antibody known as F5111 specifically directs the activities of IL-2 towards Tregs, while also extending its persistence in the bloodstream. We built on this work and designed a single-agent fusion protein that combines IL-2 with F5111 and demonstrated that our engineered therapeutic, called the F5111 immunocytokine (IC), selectively activated Tregs and protected mice against disease development in an IBD model. This project aims to advance the translation of F5111 IC, performing vital studies in animal models and patient samples that will catapult this molecule into clinical trials to directly benefit patients with IBD.

Abstract or Project Description

A performance experience for teens and young adults about navigating consent and learning embodied skills through the creative process and performance choregraphed by Yayoi Kambara, narrated and guided live by drag queen Black Benatar (aka Mx. Beatrice Thomas) and in partnership with Dance Mission Theater’s Grrrl Brigade and Ruth Asawa San Francisco School of the Arts (SOTA).

Abstract or Project Description

Kara, the sole standalone grief-focused agency in the Bay Area, annually serves 4,000 individuals with crucial bereavement support services, providing comprehensive grief support, crisis intervention and education since 1976. Through accessible, research-based interventions in English and Spanish, Kara fosters resilience, prevents and alleviates advanced reactions to loss and trauma, contributing to the well-being of the community

Abstract or Project Description

A full-length dance performance piece that will explore the storytelling capacity of Kathak from a modern perspective by challenging traditional approaches to the classical dance form and centering a wider range of movement vocabulary and narrative to expand the Kathak form.

Abstract or Project Description

To support The KHFresh Festival in honor of Kathleen Hermesdorf.

Abstract or Project Description

Keystone Symposia organizes annual peer reviewed life science conferences, bringing together researchers across academia, industry and global health to advance biomedical discovery. Conferences emphasize cross disciplinary collaboration and support emerging scientists through scholarships and career development programs.

Abstract or Project Description

Scholarships for trainees and early career researchers from underrepresented backgrounds to attend either the “Regulation of Barrier Immunity” or “Immunometabolism: From Mechanisms to Pathways to Therapies” conferences.

Abstract or Project Description

To support the Always Reading pilot in two Oakland Unified School District classrooms. The program increases access to books and families engage in weekly coaching via text to establish and maintain reading routines at home.

Abstract or Project Description

A new bilingual play by Tere Martinez, casting light on the exploitative relationship the United States has with Puerto Rico and revealing how colonization processes are still alive and well in our contemporary society. Performed in Spanish, English or Spanglish, depending on the content of the scene, the play will feature projected supertitles to ensure access and eliminate language barriers.

Abstract or Project Description

Support for Las Trampas School, Inc. to continue providing high-quality services to adults with intellectual and developmental disabilities in Contra Costa County.

Abstract or Project Description

Supports OUSD, Eduction For Change and Aspire schools to implement equitable anti-racist practices through coaching and training for leaders and educators.

Abstract or Project Description

A multi-disciplinary dance project focused on migration from Asia to North and South America and the intercultural mixing of and support between the Chinese and Peruvian communities. Featuring original music, recorded interviews and dance, the piece explores the impact of migrant communities in the Americas on culture, food, music, dance, art, language, spirituality, tradition and the building of societies and economies at large.

Abstract or Project Description

To support a range of identified needs, including funding for the bike shop, science and sailing program, ecology/vertical garden program, civics curriculum, new digital media arts program and library collection of diverse books.

Abstract or Project Description

Supports further development of the Lighthouse teacher-in-training pathway that leverages public funding to diversify the educator workforce.

Abstract or Project Description

Supports existing programs, as well as initiatives that promote community recovery from the pandemic, parent leadership and advocacy and family resource center collaboration to connect families to increased warm connections.

Abstract or Project Description

The Luggage Store, also known as The 509 Cultural Center, is a nonprofit arts organization whose mission is to foster community through multidisciplinary arts programming that promotes diversity, inclusion and dialogue among the diverse cultural communities of downtown San Francisco. They aim to reduce inter-group tensions and stereotypes through exhibitions, performances, education and public art initiatives.

Abstract or Project Description

The first play by Naomi Izuka to be produced at the Magic Theatre, “GARUDA’S WING” investigates familial and cultural history through intimate human portraits spanning two generations. The piece explores ancestry, privilege, co-optation, colonial effects and global politics.

Abstract or Project Description

A new play told through the lens of skateboarders, integrating the traditional Day of the Dead Festival Altars at Potrero del Sol Park with local skateboarding culture. Working with an ensemble of 10 talented skaters, the piece will uplift the annual Day of the Dead altars and honor the circle of life and death.